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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105807b048da88c329b5f008a36e5a235b61de0678b4eacac7e196db8d448348' 
  AND token = 'RC2lcU83Y/EF20fgl046WPmhtNU4cxLdrdCIiTU5dpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}