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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d65e257f9ade45ea2bcd186e99f26cafc304cd1cd683f952f0d1920c2deeffc' 
  AND token = '/WrXu0AaNHuNF6q9JKMj80PrjmbspDgJbuzuA3nJ5d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}