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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3674e49d534591bf5bfb2242c920af8443c7319c0a5bd7b4522fdc683a87a0c8' 
  AND token = 'lx6fxflG0rbBvpHua9z/+2bDA+SgR2UZ1EfJmmD+NSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}