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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1cf9c95ffe38ff7cdfced2d6110a72cb10cdfc7bfc1b481b75e17b6e17063e' 
  AND token = 'fjS9ocQWXSrr9hbBZI7QLlxmx18bFTyeA/eq0azkUsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}