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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f16eb5867a236d209a6b8480753942ac4b1059868886b35c9ba47f67d1cafdc' 
  AND token = '9Uph2yQum1cwqckJfx7UQ59TP887Io9sg70KJ0XZAsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}