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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27391991878013375ab2ecc04e63458415cb304ea739c44414de2fb191ce9cff' 
  AND token = 'JX7THkdMxoLDIleYZ5AtyhWMHIwZaKbcX8uaRbokD3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}