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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2305753aec3e8e057d8ac7f15aaac3d5e34d058a2e2824b89bd202a86044af' 
  AND token = '6wS/i3Jj4amVST7aEgE+gpS2SEPAzeIMrS7sykMsktI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}