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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b39c0febd271af5bf681bd14d8dcaf0133992c6e81f69beb2b2956b8270380' 
  AND token = '3nzl36KPfsZ11mbiA8OBzpMq6A32SWadqyMPYyL7f18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}