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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ed59f9737f01163bb33fbae5b6bf8cd1df2554ff21ab483bbb149cd9216273' 
  AND token = 'EIkxzH+vsU8Ia4hjGdSVA4BF4a6M/VpUR+adeltPTSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}