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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0ed032bc35258a7941018e5274d747deabfd746471659d5cb8edb9a8c1cca3' 
  AND token = 'nJNd8+PKm7oHlYBkHZ0BnDYmB9EGbZdjTz8/Jc58GjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}