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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b7ae47f803f4e8952185d00dd4f811def1d1c074588a0b844365fbbeadb5ae' 
  AND token = 'kSU9j0ryD+vX98XN2N9bbgiZczJhkM8q3DjsN+DUwiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}