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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9565ec7d462db39d6295b22807f419534f4f563e1b05ba7195fef991cb23b0' 
  AND token = 'Yjkweo1bT37XvCMl0h3lxv+8vlWBXpA/tApqB6SMs24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}