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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25186b03f1f5bcb51efe2659fb25eb2b9b4d1fdf61b47b3c68b8a083dd0be588' 
  AND token = 'SD7psCfszP5XuSTKcYRWUbn9vwVPrsXOV1Ke2rl98+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}