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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a135051800ea899d0a962f2bbfdeed01d902b3107bf2c2792e789b1cf6bc5245' 
  AND token = '44Qz3dr4rRuHIX/Mete+OQ7QfDoejEGOpwF51THeBdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}