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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106eded7a06211a64a6e27c0b22d598ee4c1bf2f22f5c072c2fd331778f728e1' 
  AND token = 'ACaBW5H0QqMapj03s3tM+EXpwkhlaUOzaBdHZj+lKaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}