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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549980375f9bf8cda35da83ad0f4e2bb406340e46ac7807d2be61242ebccdac0' 
  AND token = 'XPW/wC1v0forxEgFs7tfzGh6COSLESd+XlEXVbtvavo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}