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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0daf9b5a359f64c10133311f4c39ede55c9e43e247d243d42b66bdbb271398a3' 
  AND token = 'eEyX4ehHCRDARR5fBo2h1uHUGL1gmV8eSVBlybtN+1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}