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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f23d1763699c4520e29b438f3ad6e3e375235219c51ade64050234b5f2c5e4a' 
  AND token = 'L4vz2c+6BbvjBltJiEsl7Svh9YLODCYTk/nTAJbY8SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}