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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4429e41ff09d27f9b4a4a32e4a0fdcb94f49029d27466815e042cfe7552248b' 
  AND token = 'L1KOvzZdA6pq1InDrdgKAnK1jQM5tE8H41dDG6Aa/LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}