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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395246a70fae77f0be1aa1664b196aaeb4e2a5c2510bca88b1aafdc8d0af1993' 
  AND token = 'vZ8Po9ww+MEP+yFEZ655wPL8lDqcPZUsgwkCaZrIUjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}