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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dd0d5878dcd7cee22a6be188c725dad89cb593573e5e02263c6b244e7e90b5' 
  AND token = '/5SQJKXdGWHcNpc0NWr4DlhjA/QAtGTfhBzsvVyFdZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}