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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ad5ca119362717365cbd4ab16f186fa6367627ee3285ec789574a606c0d946' 
  AND token = 'eIE3byv2cEtYtDvI6r5HTb2GbDSCJ4pEVEXU2qVFaV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}