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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5fff3d1bcad2e6665a4829c8e9174b6f76249b98bb2dc13c884ccc8a1661300' 
  AND token = '3V0vukji6t/lYKO0DaQVl7JVcaab4dYkxkKekarHt9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}