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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ec800805ee629353e896697d70a62f119c0263890ee35a6202c9e1c3764f60' 
  AND token = 'nPFRYJni/yxRrfgxQTfMtu+5Udk39tXw2iOzVc8ffoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}