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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b808e315bd8e5828a2d796107ac41ba4b682f9a25cc252650b559725bf34b761' 
  AND token = 'pR3+DF/Tdhs23R4U4o+Y42g+ClrH0dPc4X/gwkCL1ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}