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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd8f36f7eadaa3187b4ad1d82203d328a1c52207eaa73e5537b3de887f9dac53' 
  AND token = 'aQqBc6rmVm1PgtuZDnPE8TamMMBtsTt9M7d6pZbg8y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}