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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499a390c2475b0275b70456427092758900c7984c918fd3f5af8bd11d32df4b3' 
  AND token = 'yAK+xIRuWBq9lwg35cytuArh2RblXOfOsW4C24FGoEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}