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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100eeefa91ae686354b9329afb92049f9a6bf4bdf0fd03abd592ed01d64e3716' 
  AND token = 'fISTuYyKCW4L17uITT6N6eHdcG+6omQxAlZS5yvWwiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}