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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5331f710c6313b424bc842cb32f874516158ff3ec12e3f1b03b5362ed0d5b275' 
  AND token = 'grQpQL5u9kA9aKb2PqAVDA5sYeveS1fo5fnc9hoWjjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}