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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7998370d25e9c91802b816011f26feb4da1497324d8dd60020940a886c5e9d29' 
  AND token = 'sKx8YTsY2F41wlooOBCYUhIdXvUHb8EUWti6lXdByCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}