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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c33a4c4b568a188f9bcfb84ce78711094eb0ddddd04844108bb4e27de7623b' 
  AND token = 'ASZHpjMg7DpAnZRXfSMkEid+yiIEpjMIC6wP4ntOBBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}