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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a2295e71e9ee2a1f3e2a07fb1fb4125685db49f063b6ca7e7cae1b12cb8cf4' 
  AND token = 'JwPxWHPN73V2R4cZ/oJ371HIPpmU5+uPZqJMjEdPdAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}