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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38df91a6c34ca94c645b9f3bf3c388391c07a3dfeecf5a5a0beddd86b53fd619' 
  AND token = 'jrdwlnKqnShJfGUK5HqycIgQHys4sPcRXhgKUEAZOIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}