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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d146644b56c7bea8d47cef28f1e15874a9239e57e36df9f95c1fff1aff2ce00' 
  AND token = '6hatlMLxqAwiefKszm+NA9uaAqSRRQt/2eekkrXVdmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}