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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9112f40850ad83eb8ad2d0729222362a05ecde5462b6625bac33e024c87a744f' 
  AND token = 'osJNLdRTZKF1vFX6S3HhgX4/6qp7FkJ18pX/NMI8VSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}