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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243a46088039bd1752f7df09f6717161924ad08500864da0fda9d8407f28a4b5' 
  AND token = 'Kq5GE9fSySoy3/LG1+2a7yZH8hYO9TlJfRppEW4j5gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}