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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd47b04150b354bc7edf8bd22d2fd723b3cbefb46e2a442b4f4684b434625a590' 
  AND token = 'yMLAw7Q0t3W6WPukbdcRwkU6/Nz3vc57Z5pLJHNzGTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}