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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c01ebe511fceffbc305f7cd5257d74773e91b70e35493599f2a6ec41f70b78' 
  AND token = 'rQ9fwPLJ1eMpN94oUQXpAqFNPmXD58gp6sr1FXEADt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}