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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28cd2d5a3b0d4a6d685f1c1b0b9e0dfc2af86c0ba4bdd6dbca6d76399c01abe1' 
  AND token = '2tWdl/PrqOf9D1HQzNSwHSVqU/BU2rh5joHD2Qs3agQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}