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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b26e87120790a227f0d9c349441849d8cbc4ddd1e60fc475a6a83b23e0e3e20' 
  AND token = 'nPJ5uePQHkQDUjnPo4dQx/GNLAdFjsrO1WbtM+gqjFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}