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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4343c73df9f2b22d81d36220cadea92cf7e0ad835b3264aa61b5a4d5fd30da7c' 
  AND token = '4W9ja8+TZYRVq7U0fcmNxMvllOvxbnoJTUnRKj9HPKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}