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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0d5679564024a83342e1f386e0f117710cddb9eabb1da32691c06306800fe84' 
  AND token = '1mc5/aC+8+2tv5KE/AnymY4zNLsOk2DSObyE+bAWA2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}