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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5df60be59654c3bde6e5d57d89145d19d17fb93af018a1600d4a1f4326e6cc' 
  AND token = 'UC9t/9W+/Oo+cD9+eTk3UvQLf0CYDajSbXKSev9PgsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}