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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f45b5606705910896477ec90d9eb8bdb6e179ceb6a3608ecd88731f133f74e' 
  AND token = 'ecy0RU6Mcb6p4EvveUZT3FUoBeTAe96NnR7o5l3yk/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}