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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11fd4ad4ec10a13f20b4317ce3000f367f9e27e72aea5be544f0cd893c112f48' 
  AND token = 'RGrRIC3Oto6Oq3ZSKksO7xVgHrHt4TTOD0Lg3sYOuzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}