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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5deff24135d286136706dfc5370bc74e3d8330e7c2d5d3e604c616a99a9680' 
  AND token = 'j1bR9bzO2RepxX/U/lMbQTzBt1QYbS3dCzjGNbUrOec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}