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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b58905d1e749ef573bf14cee7e782c7f110ad73be8c545808ee9fb730189dd6' 
  AND token = 'nZGCGRDV2jv5xwDFBxR0D6uVF+eeLOt8+BtryqEe6Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}