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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65acaab6470fcaec08ef55214970b50452790e1619df6cbea1fcef78cce08f5f' 
  AND token = 'kp9iZwyLLA2h07OY4nYNk/ElY4YwHduHF/kfbpHbjO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}