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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e520453aa0f4439fdafb55fdebfa535d07d40a58f359d31b3eae022083afda' 
  AND token = 'YyKMRsYKeQGu4h6WMG3y4IMlgYmKIs0ahMO6dEVPRYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}