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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266c954ea4a2648561c3c08af5afa2dc85e65524a5bc7b1e574606ca2571eb54' 
  AND token = '2cONI1qePCP1gfQ4SSa2jtVpw+4Cygm0p5c5/2PLiuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}